Evaluation of the PaO2/FiO2 Ratio as a Risk Factor for Hypoxemia against Septicemia Mortality in Children who Treated at Dr. Soetomo General Hospital

Background: Severe septicemia can result in impaired oxygen perfusion to the tissues. The PaO2/FiO2 ratio(P/F ratio) is one of measurement parameters for hypoxemia. This study aims evaluate P/F ratio asa risk factor hypoxemia against mortality children.Method: An observational with a prospective cohort design was conducted. Thirty-six patients withsepticemia, consisting 18 who living (survivor) and died (non-survivor). TheP/F obtained based on blood gas analysis carried out first 24 hours treatment recorded onmedical records calculated manually. has an area under curve (AUC) 0.83 (95%CI 0.71–0.95) cut-off 226. Septicemia children < 226 have riskof up 6.9 times (RR 6.9; 95% CI 1.719-27.957; p= 0.005) sensitivity 72.70%; specificity 72.20%;PPV 76.19%; NPV 68.42%. mean non-survivor group significantly lower than thesurvivor 161.60 (95% 1.05) compared 391.09 2.13); 0.005).Conclusion: be mortality.